Anastrozole 1mg TabletsOut of date information, search another
This product is known as the above names but will be referred to as Arimidex throughout this leaflet.
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor, or pharmacist or nurse.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor, or pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.
1. What Arimidex is and what it is used for
2. What you need to know before you take Arimidex
3. How to take Arimidex
4. Possible side effects
5. How to store Arimidex
6. Contents of the pack and other information
Arimidex contains a substance called anastrozole. This belongs to a group of medicines called ‘aromatase inhibitors'. Arimidex is used to treat breast cancer in women who have gone through the menopause. Arimidex works by cutting down the amount of the hormone called estrogen that your body makes. It does this by blocking a natural substance (an enzyme) in your body called ‘aromatase'.
Do not take Arimidex
• if you are allergic to anastrozole or any of the other ingredients of this medicine (listed in section 6).
• if you are pregnant or breast-feeding (see the section called ‘Pregnancy and breast-feeding').
Do not take Arimidex if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Arimidex.
Talk to your doctor, or pharmacist or nurse before taking Arimidex
• if you still have menstrual periods and have not yet gone through the menopause.
• if you are taking a medicine that contains tamoxifen or medicines that contain estrogen (see the section called ‘Other medicines and Arimidex').
• if you have ever had a condition that affects the strength of your bones (osteoporosis).
• if you have problems with your liver or kidneys.
If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking Arimidex.
If you go into the hospital, let the medical staff know you are taking Arimidex.
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Arimidex can affect the way some medicines work and some medicines can have an effect on Arimidex.
Do not take Arimidex if you are already taking any of the following medicines:
• Certain medicines used to treat breast cancer (selective estrogen receptor modulators), e.g. medicines that contain tamoxifen. This is because these medicines may stop Arimidex from working properly.
• Medicines that contain estrogen, such as hormone replacement therapy (HRT).
If this applies to you, ask your doctor or pharmacist for advice.
Tell your doctor or pharmacist if you are taking the following:
• A medicine known as an ‘LHRH analogue'. This includes gonadorelin, buserelin, goserelin, leuprorelin and triptorelin. These medicines are used to treat breast cancer, certain female health (gynaecological) conditions, and infertility.
Do not take Arimidex if you are pregnant or breast-feeding. Stop Arimidex if you become pregnant and talk to your doctor.
Ask your doctor or pharmacist for advice before taking any medicine.
Arimidex is not likely to affect your ability to drive or use any tools or machines.
However, some people may occasionally feel weak or sleepy while taking Arimidex.
If this happens to you, ask your doctor or pharmacist for advice.
Arimidex contains lactose which is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
Always take Arimidex exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
• The recommended dose is one tablet once a day.
• Try to take your tablet at the same time each day.
• Swallow the tablet whole with a drink of water.
• It does not matter if you take Arimidex before, with or after food.
Keep taking Arimidex for as long as your doctor or pharmacist tells you to. It is a long-term treatment and you may need to take it for several years. Check with your doctor or pharmacist if you are not sure.
Arimidex should not be given to children and adolescents.
If you take more Arimidex than you should, talk to a doctor straight away.
If you forget to take a dose, just take your next dose as normal.
Do not take a double dose (two doses at the same time) to make up for a forgotten dose.
Do not stop taking your tablets unless your doctor tells you to.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
• Hot flushes.
• Feeling sick (nausea).
• Skin rash.
• Pain or stiffness in your joints.
• Inflammation of the joints (arthritis).
• Feeling weak.
• Bone loss (osteoporosis).
• Loss of appetite.
• Raised or high levels of fatty substance known as cholesterol in your blood. This would be seen in a blood test.
• Feeling sleepy.
• Carpal tunnel syndrome (tingling, pain, coldness, weakness in parts of the hand).
• Tickling, tingling or numbness of skin, loss/lack of taste.
• Being sick (vomiting).
• Changes in blood tests that show how well your liver is working.
• Thinning of your hair (hair loss).
• Allergic (hypersensitivity) reactions including face, lips, or tongue.
• Bone pain.
• Vaginal dryness.
• Bleeding from the vagina (usually in the first few weeks of treatment - if the bleeding continues, talk to your doctor).
• Muscle pain.
• Changes in special blood tests that show how your liver is working (gamma-GT and bilirubin).
• Inflammation of the liver (hepatitis).
• Hives or nettle rash.
• Trigger finger (a condition in which your finger or thumb catches in a bent position).
• Increased amounts of calcium in your blood. If you experience nausea, vomiting and thirst, you should tell your doctor, or pharmacist or nurse as you may need to have blood tests.
• Rare inflammation of your skin that may include red patches or blisters.
• Skin rash caused by hypersensitivity (this can be from allergic or anaphylactoid reaction).
• Inflammation of the small blood vessels causing red or purple colouring of the skin.
Very rarely symptoms of joint, stomach, and kidney pain may occur; this is known as ‘Henoch-Schonlein purpura'.
• An extremely severe skin reaction with ulcers or blisters on the skin. This is known as ‘Stevens-Johnson syndrome'.
• Allergic (hypersensitivity) reactions with swelling of the throat that may cause difficulty in swallowing or breathing.
This is known as ‘angioedema'.
If any of these happen to you, call an ambulance or see a doctor straight away - you may need urgent medical treatment.
Arimidex lowers the amount of the hormone called estrogen that is in your body. This may lower the mineral content of your bones. Your bones may be less strong and may be more likely to fracture. Your doctor will manage these risks according to treatment guidelines for managing bone health in women who have gone through the menopause. You should talk to your doctor about the risks and treatment options.
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine.
Yellow Card Scheme
Irish Medicines Board
Kevin O'Malley House
Tel: +353 1 6764971
Fax: +353 1 6762517
• Arimidex should not be stored above 30°C.
• Do not use after the expiry date printed on the carton, label or blister strip. The expiry date refers to the last day of that month.
• KEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN.
• If your doctor tells you to stop taking the tablets, please take them back to the pharmacist for safe disposal. Only keep the tablets if your doctor tells you to.
• If the tablets become discoloured or show any other signs of deterioration, you should consult your pharmacist who will advise you what to do.
• Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Your medicine is called Arimidex. Each tablet contains 1mg of the active ingredient, anastrozole in a white, round, film-coated tablet marked with a logo on one side and marked with 'Adx 1' on the other side.
Arimidex also contains the following inactive ingredients:
Lactose monohydrate, macrogol 300, magnesium stearate, hypromellose, povidone, sodium starch glycollate and titanium dioxide (E171).
Arimidex are available as calendar blister packs of 28 and 84 tablets.
POM PL No: 6464/1842
This product is manufactured by AstraZeneca UK Ltd, Silk Road Business Park, Macclesfield, Cheshire, United Kingdom and is procured from within the EU and repackaged by the Product Licence holder: Waymade Plc, Miles Gray Road, Basildon, Essex SS14 3FR
Leaflet revision and issue date (Ref.) 24.06.2014
Arimidex® is a registered trademark of ASTRAZENECA LIMITED