Angiozem 120 XlOut of date information, search another
PACKAGE LEAFLET: INFORMATION FOR THE USER
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
- If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
In this leaflet:
1. What Uard is and what it is used for
2. Before you take Uard
3. How to take Uard
4. Possible side effects
5. How to store Uard
6. Further information
1. WHAT UARD IS AND WHAT IT IS USED FOR
Uard contains diltiazem hydrochloride as the active substance. Diltiazem hydrochloride belongs to a group of medicines known as calcium channel blockers.
Uard is used to treat high blood pressure (hypertension). It can also be used to prevent and treat a certain type of chest pain known as angina. Uard works by opening up blood vessels so that blood passes through them more easily, and so reduces blood pressure and chest pain in angina.
2. BEFORE YOU TAKE UARD
Uard is not suitable for use in children.
Do not take Uard
- if you are allergic (hypersensitive) to diltiazem hydrochloride or any of the other ingredients of Uard (see Section 6 for
a full list of ingredients)
- if you are pregnant or could become pregnant
- if you are breast-feeding
- if you have a very slow heart rate, less than 50 beats per minute (marked bradycardia)
- if you have a condition called sick sinus syndrome (an abnormality of heart rate or heart rhythm)
- if you suffer from left-sided heart failure (left ventricular failure), with symptoms such as shortness of breath and swelling of the ankles
- if you suffer from second or third degree heart block (this is a problem with the electrical impulses of the heart) unless you have a working pacemaker fitted
- if you are due to have an operation where you might be given a muscle relaxant called dantrolene (most likely to be administered in hospital under general anaesthesia)
Talk to your doctor before taking this product if any of the above apply to you.
- if you have any liver or kidney problems
- if you have a slow heart rate (mild bradycardia)
- if you have any heart problems such as heart failure or first degree heart block (a problem with the electrical impulses of the heart)
If any of the above apply to you, it is important that you tell your doctor or pharmacist before taking Uard and they will decide what to do. It may still be safe for you to take Uard.
Please tell your doctor or pharmacist if you are taking or have recently taken any of the following medicines, including those medicines obtained without a prescription:
- alpha-blockers, such as doxazosin or prazosin (medicines used for high blood pressure or prostate enlargement in men)
- amiodarone (used to treat abnormal heart rhythms)
- rifampicin (used to treat bacterial infections)
- carbamazepine, phenytoin or primidone (used in epilepsy)
- atazanavir or ritonavir (used to treat viral infections)
- sleeping tablets or sedatives
- beta-blockers, such as propranolol or atenolol (medicines used to treat high blood pressure or other heart conditions)
- digoxin (used to treat heart failure and abnormal heart rhythms)
- ciclosporin, sirolimus or tacrolimus (used to prevent rejection of a transplanted organ)
- cilostazol (used to improve blood circulation to the legs)
- theophylline (used to treat breathing problems)
- general anaesthetics
- tricyclic antidepressants, such as imipramine
- antidepressants known as monoamine oxidase inhibitors/MAOIs, such as moclobemide or phenelzine
- itraconazole (used to treat fungal infections)
- mefloquine (used for treating and preventing malaria)
- corticosteroids, sometimes simply referred to as steroids, such as hydrocortisone or prednisolone (they may be prescribed in many different illnesses but their main action is in controlling inflammation)
- simvastatin, atorvastatin or lovastatin (medicines for lowering cholesterol)
- nifedipine (used to treat high blood pressure and angina)
- lithium (used in cases of marked mood changes or mania)
- nitrate medicines, such as glyceryl trinitrate or isosorbide mononitrate (used to treat angina)
- ulcer-healing medicines, such as cimetidine.
It may still be safe for you to take Uard; your doctor or pharmacist will be able to advise you further.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Taking Uard with food and drink
Taking Uard with food and drink does not affect the way the product works.
Pregnancy and breast-feeding
Do not take Uard if you are pregnant, trying to become pregnant or if you are breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine during pregnancy or while breast-feeding.
Driving and using machines
It is safe to drive while taking this medicine, however it may make you feel faint or dizzy. If you find that you are affected you should not drive or operate machinery.
These capsules contain sucrose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
3. HOW TO TAKE UARD
Always take Uard exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
The usual dose for adults is between 180mg and 300mg of diltiazem given once a day. This dose may be reduced to 120mg once a day, for elderly patients, or patients with kidney or liver disease.
The label on the carton will tell you how many capsules you should take and when. This product should be taken orally (by mouth). Swallow the capsules whole with a drink of water. Do not crush or chew the capsules.
change in the way things tas feeling sick (nausea) loss of appetite being sick (vomiting) constipation diarrhoea weight gain skin rash
sensitivity to sunlight enlargement of breast tissue in men jaundice (yellowing of the skin and the whites of the eyes)
hepatitis (inflammation of the liver)
If you take too many capsules, contact your nearest hospital casualty department or doctor immediately. Take this leaflet and any remaining capsules with you to show the doctor.
If you forget to take Uard
If you miss a dose but remember within 12 hours of the usual time, take it when you remember. If you remember more than 12 hours after your usual time, leave out this dose completely and carry on with the next dose when it is due. Do not take a double dose to make up for a forgotten dose.
If you stop taking Uard
Do not stop taking Uard without consulting your doctor. Stopping suddenly might make your angina worse.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Uard can cause side effects, although not everybody gets them.
If you notice:
- slowing of the heart rate (bradycardia)
- irregular heart rate
- severe skin rashes with skin flaking
Stop taking Uard and contact your doctor immediately.
The following side effects have also been reported:
- swelling of the legs, (this is more common in elderly patients and may be worse with higher doses)
- low blood pressure
- flushing (when your face, ears, neck and, occasionally, your upper chest, becomes red in colour)
- generally feeling unwell
- swollen gums If you consider any of the side effects to be serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE UARD
Keep out of the reach and sight of children.
Do not use Uard after the expiry date which is stated on the carton and blister foil. The expiry date refers to the last day of that month.
Do not store your capsules above 25‘C. Store in the original packaging in order to protect the capsules from light and moisture.
Do not use Uard if you notice that the packaging or any of the capsules are damaged.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. FURTHER INFORMATION
The active substance is diltiazem hydrochloride.
Uard comes in four different strengths of capsule:
- Uard 120XL which contains 120mg of diltiazem hydrochloride per capsule.
- Uard 180XL which contains 180mg of diltiazem hydrochloride per capsule.
- Uard 240XL which contains 240mg of diltiazem hydrochloride per capsule.
- Uard 300XL which contains 300mg of diltiazem hydrochloride per capsule.
The beads in the capsule shells also contain other ingredients: ammonio methacrylate copolymer types A and B, paraffin, talc, sucrose and starch.
The capsule shells are made of gelatin and may contain, depending on the strength of the capsule, the following colouring agents: erythrosine (E127), indigotine (E132), titanium dioxide (E171), red iron oxide (E172), black iron oxide (E172) and yellow iron oxide (E172).
The ink on the capsule shells contains shellac, black iron oxide (E172) and propylene glycol.
- Uard 120XL are hard gelatin capsules, with a brownish-red cap and an orange body, with "DIL 120" overprinted in black ink.
- Uard 180XL are hard gelatin capsules, with a pink cap and a grey body, with "DIL 180" overprinted in black ink.
- Uard 240XL are hard gelatin capsules, with a light blue cap and body, with "DIL 240" overprinted in black ink.
- Uard 300XL are hard gelatin capsules, with a light blue
cap and a white body, with "DIL 300" overprinted in black ink.
Uard 120XL, 180XL, 240XL and 300XL are packaged in blister packs containing 28 capsules.
Marketing Authorisation Holder Galen Limited Seagoe Industrial Estate Craigavon, BT63 5UA UK
Almac Pharma Services Limited Almac House
20 Seagoe Industrial Estate Craigavon, BT63 5QD UK
Ennogen Healthcare Limited Unit G4, Riverside Industrial Estate Riverside Way Dartford, DA1 5BS UK
This leaflet was last approved in November 2012 Uard is a trade mark.