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Atenolol 50mg Tablets

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•    Mood changes

•    Nightmares

•    Confusion

•    Mental problems

•    Hallucinations and visual disturbances

•    Dizziness

•    Headache

•    Tingling or numbness of the skin

•    Dry eyes or mouth

•    Hair loss

•    Flaky, scaly skin

•    Low blood pressure leading to fainting when you stand up

•    Liver problems

•    Impotence

•    Worsening of the following conditions:

-    Psoriasis

-    Heart failure

-    Heart block

-    Asthma or breathing problems

-    Poor circulation (e.g. leg cramps on walking)

Very rare (seen in less than 1 in 100,000 patients)

•    An increase in ANA (antinuclear antibodies) which may show up in blood tests

If you experience any of these side effects and they get serious or if you notice any side effects not listed in this leaflet, tell your doctor or pharmacist.

5.    STORING ATENOLOL TABLETS

Keep out of the reach and sight of children.

Do not store above 25 °C.

Do not use after the expiry date stated on the label.

Store in the original packaging.

Do not dispose of medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6.    FURTHER INFORMATION What Atenolol Tablets contain

Each tablet contains either 50 mg or 100 mg of the active substance atenolol. The other ingredients are Maize starch, Heavy magnesium carbonate, Gelatin, Magnesium stearate, Sodium lauryl sulphate.

What Atenolol Tablets look like and contents of the pack

The tablets are white and round shaped. They have a score line on one side and' K' on the other. Both strengths come in packs of 28.

This leaflet was last updated in May 2011 PL 37235/ 0006 PL 37235/ 0007

M A Holder and Manufacturer:

Pharma Roth GmbH

Gustav Stresemann Ring -1 65189, Wiesbaden, Germany.

/T\    xxxxxxx

Atenolol 50mg and lOOmg Tablets

Read all of this leaflet carefully before you start taking this medicine

•    Keep this leaflet. You may need to read it again.

•    If you have further questions, please ask your doctor or pharmacist.

•    This medicine has been prescribed for you. Do not pass it on to others as it may harm them, even if their symptoms are the same as yours.

•    If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

In this leaflet:

1.    What Atenolol tablets are and what they are used for

2.    Before you take Atenolol tablets

3.    How to take Atenolol tablets

4.    Possible side effects

5.    Storing Atenolol tablets

6.    Further Information

1.    WHAT ATENOLOL TABLETS ARE AND WHAT THEY ARE USED FOR

Atenolol belongs to a group of drugs called beta-blockers. It affects the heart and circulation. It works by making your heart beat more slowly and with less force.

Atenolol tablets are used to treat:

•    high blood pressure (hypertension)

•    chest pain (angina)

•    irregular heart beat (arrhythmias)

•    heart attack (myocardial infarction) in the early stages of treatment

2.    BEFORE YOU TAKE ATENOLOL TABLETS Do not take these tablets if you:

•    are allergic (hypersensitive) to Atenolol or any of the other ingredients of these tablets.

•    have an abnormally slow or irregular heartbeat

•    suffer from shock caused by heart disease or heart attack

•    have very low blood pressure (hypotension)

•    have abnormal levels of acid in your blood (metabolic acidosis)

•    suffer from very poor circulation (symptoms include leg cramps when walking)

•    suffer from second or third degree heart block (a disease of the electrical system of the heart)

•    have an untreated tumour on your adrenal gland (phaeochromocytoma)

•    suffer from heart failure which is not under control

Take special care with Atenolol Tablets

Tell your doctor before you start to take your tablets if you:

•    are currently receiving treatment for heart failure

•    have a type of chest pain called Prinzmetal's angina

•    Have a mild fonn of poor circulation

•    suffer from first degree heart block (a disease of the electrical system of the heart)

•    have diabetes. Atenolol may mask your normal response to low blood sugar, which usually involves an increase in heart rate

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•    have a condition caused by an overactive thyroid gland (thyrotoxicosis). Atenolol may hide the symptoms of thyrotoxicosis.

•    Have a low heart rate

•    Are aged over 65. You may be given a lower dose.

•    Suffer from poor kidney function. You may be given a lower dose.

•    Are receiving treatment for a tumour on your adrenal gland (phaeochromocytoma)

•    You have asthma or you get allergic reactions, for example, to insect stings. If you have ever had asthma or wheezing, you should not take this medicine unless you have discussed these symptoms with the doctor who first gave you the tablets.

Taking other medicines:

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even those that you have purchased yourself, without prescription.

In particular, tell your doctor if you are taking any of the following:

•    Clonidine (for high blood pressure or migraine). If you are taking clonidineand Atenolol together, you must not stop taking clonidine unless your doctor tells you to do so. If you have to stop taking clonidine, your doctor will give you careful instructions about how to do it.

•    Digoxin (used to treat heart problems)

•    Adrenaline (used to stimulate the heart)

•    Ibuprofenand indometacin (for pain and inflammation)

•    Insulin and other medicine to treat diabetes

•    Medicines for heart rhythm problems e.g. disopyramide and amiodarone

•    Medicines for high blood pressure or angina (chest pain) such as verapamil, diltiazem or nifedipine

Operations

If you go into hospital to have an operation, tell the anaesthetist or medical staff that you are taking Atenolol. This is because you can get low blood pressure (hypotension) if you are given certain anaesthetics while you are taking Atenolol.

Pregnancy and Breast-feeding

Talk to your doctor before taking these tablets if you are pregnant, planning to become pregnant or are breast-feeding, as this medicine may harm your baby.

Driving and using machines:

Your tablets are unlikely to affect your ability to drive or to use machinery. Some people may occasionally feel dizzy, tired or have visual disturbances when taking Atenolol. If this happens to you, do not drive or use machines.

3. HOW TO TAKE ATENOLOL TABLETS

Always take your tablets exactly how your doctor has told you to. Check with your doctor or pharmacist if you are unsure.

Swallow the tablets with a drink.

Your doctor will tell you how many tablets to take each day and when to take them, depending on your condition. Also, read the label on the container. Your pharmacist can help you if you are not sure.

ZTS    XXXXXXX

Atenolol tablets are not recommended for use in children.

Usual dosage for an adult

•    To treat high blood pressure (hypertension): 50mg to lOOmga day

•    To treat chest pains (angina): lOOmg once a day or 50mg twice a day

•    To treat irregular heart beat (arrhythmias): 50mg to lOOmga day

•    After a heart attack: 50mg every 12 hours on the first day, thereafter lOOmg daily

The dosage may be lower for elderly patients or patients with kidney problems.

If you have the impression that the effect of Atenolol tablets is too strong or too weak, talk to your doctor or pharmacist

If you take more Atenolol tablets than you should

If you accidentally take too many tablets, either call your doctor straight away, or go to your nearest hospital casualty department. Always take any tablets you have left, the container and the label with you, so that the medical staff know exactly what you have taken.

If you forget to take Atenolol tablets

If you forget to take your tablets at the right time, take them when you remember and then take your next dose at the usual time. Don't take two doses at the same time. If you are worried, ask your doctor or your pharmacist for advice.

Effects when treatment with Atenolol tablets is stopped

Do not stop taking your tablets without talking to your doctor first. In some cases, you may have to stop taking them gradually.

4. POSSIBLE SIDE EFFECTS

Like all medicines, Atenolol can cause side effects.

Serious Allergic Reactions

•    Swelling of the face, mouth or throat which may cause difficulty breathing

•    Red, itchy rash

If you experience any of these side effects tell your doctor or go to your nearest casualty department

Other possible side effects

If you experience any of the side effects listed below and they get serious, tell your doctor or pharmacist.

Common effects (seen in between 1 in 100 and 1 in 1000 patients)

•    Slow heart rate

•    Cold hands and feet

•    Stomach problems such as diarrhoea or vomiting

•    Tiredness

Uncommon effects (seen in between 1 in 1000 and 1 in 10,000 patients)

•    Sleep problems

•    Liver enzyme increases which may have an effect on some medical tests Rare effects (seen in between 1 in 10,000 and 1 in 100,000 patients)

•    Skin rashes including a purple rash due to bleeding under the skin

•    Reduction in blood platelets, which increases the risk of braising and bleeding

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