Atropine Sulphate Injection Bp
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Read all of this leaflet carefully before you are given Atropine Injection
• Keep this leaflet. You may need to read it again
• If you have any further questions, please ask your doctor or nurse
• If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or nurse
In this leaflet:
1. What Atropine Injection is and what it is used for
2. Before Atropine Injection is given
3. How Atropine Injection is given
4. Possible side effects
5. How to store Atropine Injection
6. Further information
This leaflet contains a summary of the information available for this medicine. You should ask your doctor or nurse if you are unsure about any aspect of this medicine.
1. What Atropine Injection is and what it is used for
Atropine belongs to a group of medicines called antimuscarinics. These medicines are often used in anaesthesia to reduce the flow of saliva and other body fluids. Atropine may also act on the vagus nerve (a nerve that sends nformation from the brain to other parts of the body). This helps to make the heart beat faster.
Atropine Injection is used to raise the heart rate if it has become too slow after a heart attack or as a result of taking beta-blocker drugs.
Atropine is also used to reduce fluid in the lungs during general anaesthesia.
2. Before having Atropine Injection
You should not be given Atropine Injection if:
• you have problems with your prostate, often indicated by a difficulty passing urine, particularly in elderly men
• you have glaucoma (increased pressure in the eye)
• you have difficulty having bowel movements because you have paralysis of the bowel (paralytic ileus)
• you are breast-feeding.
Take special care with Atropine Injection Tell your doctor if:
• you have a fever
• you have a condition called pyloric stenosis which means that it is difficult for food to move from your stomach into the small intestine and which causes pain or vomiting
• you have an inflamed gut with symptoms of blood and mucous in the faeces
• you have a heart disorder
• you have acid reflux with heartburn (gastro-oesophageal reflux).
f any of the above applies to you, please tell your doctor. Taking other medicines
Please tell your doctor or nurse if you are taking, or have ecently taken, any other medicines including medicines obtained without prescription.
Other medicines which may interact with Atropine Injection are:
• medicines used to treat allergies (antihistamines)
• medicines used to treat depression (tricyclic antidepressants)
• medicines used to treat schizophrenia and other mental disorders (butyrophenones and phenothiazines)
• amantidine (a medicine used in the treatment of Parkinson's disease)
• metoclopramide (a medicine used to stop you being sick).
Pregnancy and breast-feeding
Tell your doctor if you are pregnant or trying to become pregnant before you are given this medicine. You should not oe given this medicine if you are breast-feeding.
Driving and using machines
Atropine Injection may affect your vision or your mood. If you feel at all unwell you should not drive or use machinery.
3. How Atropine Injection is given
This medicine is an injection that will be given to you by a doctor. Your doctor will determine the dose you require. It will be given under the skin, into a vein or into a muscle.
Adults (including the elderly):
As treatment to increase heart rate:
• 100 micrograms into the vein or under the skin, followed by further doses of 100 micrograms if necessary.
For reducing fluid in the lungs during an operation:
• 300 - 600 micrograms under the skin or into a muscle 30 minutes before the anaesthetic
• Alternatively, 300-600 micrograms may be given into a vein immediately before the anaesthetic.
Children:
For drying fluids during an operation (given 30 minutes before the anaesthetic): nfants
• Premature Up to 60 micrograms given under the skin
• Full term Up to 100 micrograms given under the skin
• 6-12 months Up to 200 micrograms given under the skin
Older Children
• Up to 20 micrograms per kg of body weight given into a muscle.
If you think you have been given too much Atropine Injection
This medicine is given to you by your doctor so it is unlikely you will receive too much. Your doctor has information on how to recognise and treat an overdose. If you are concerned about your treatment, please talk to your doctor.
4. Possible side effects
_ike all medicines Atropine Injection can cause side effects, although not everybody gets them.
Possible side effects include:
• excitement or delirium
• dilated pupils
• fast pulse
• hot flush
• dry skin, dry mouth, thirst
• an irregular heart beat (arrhythmias)
• difficulty passing water
• constipation.
Rare side effects include:
• fever
• a feeling of confusion
• a rash.
f any of these side effects get serious, or you notice any other side effects not listed in this leaflet, please tell your doctor or nurse.
5. How to store Atropine Injection
Keep out of the reach and sight of children You should not be given this medicine if it has passed the expiry date shown on the ampoule label. The expiry date efers to the last day of that month. The doctor or nurse will check that the product has not passed this date.
Store below 25°C.
6. Further Information
What Atropine Injection contains:
The active ingredient is Atropine Sulphate 0.06% w/v.
The other ingredients are sodium chloride and water for injections. It may also include sodium hydroxide and sulphuric acid.
What Atropine Injection looks like and contents of the pack:
Atropine Injection is a clear, colourless solution supplied in glass ampoules each containing 1ml. The ampoules are supplied to your pharmacist or doctor in packs of 10.
The Marketing Authorisation Holder and Manufacturer:
Martindale Pharmaceuticals. Bampton Road, Harold Hill,
Romford, RM3 8UG.
Product Licence Number: PL 01883/6169 Date of last revision: July 2012
If you would like any more information, or would like the leaflet in a different format, please contact Medical Information at the above address.
Martindale JLJj Pharmaceuticals fVw
_Bampton Road, Harold Hill, Romford, RM3 8UG, United KinqdomI
C91 342 ___________i