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Artwork C n aati ve □ a s i a n s	Artwork No.		260913/2			Colours Used
	Customer		Relon Chem		■	Balck
	Description		Candesartan Celexitil 8mg Leaflet		■	Keyline (not to print)
	Market		UK
	Language		English
i/i	Size		140 x 540 mm
	Min. Font Size		9 pt
	Page No.		1 of 1
e-mail : prasad.pdp@gmail.com Ph: +91-9845609386	Version No.		1
	Date		26-09-13
	Software		Illustrator 10
Packaging Development		Quality Assurance (QA)		Quality Control (QC)		Production

What is in this leaflet:

1.    What Candesartan cilexetil is and what it is used for

2.    What you need to know before you take Candesartan cilexetil

3.    How to take Candesartan cilexetil

4.    Possible side effects

5.    How to store Candesartan cilexetil

6.    Contents of the pack and other information

1.    WHAT CANDESARTAN CILEXETIL IS AND WHAT IT IS USED FOR

The name of your medicine is Candesartan cilexetil. The active ingredient is candesartan cilexetil. This belongs to a group of medicines called angiotensin II receptor antagonists. It works by making your blood vessels relax and widen. This helps to lower your blood pressure. It also makes it easier for your heart to pump blood to all parts of your body.

This medicine is used for:

•    treating high blood pressure (hypertension) in adult patients.

•    treating adult heart failure patients with reduced heart muscle function, in addition to Angiotensin Converting Enzyme (ACE) inhibitors or when ACE inhibitors cannot be used (ACE inhibitors are a group of medicines used to treat heart failure).

2.    BEFORE YOU TAKE CANDESARTAN CILEXETIL

Do not take Candesartan cilexetil

•    if you are allergic (hypersensitive) to candesartan cilexetil or any of the other ingredients of Candesartan cilexetil (see Section 6).

•    if you are more than 3 months pregnant (it is also better to avoid Candesartan cilexetil in early pregnancy see pregnancy section).

•    if you have severe liver disease or biliary obstruction (a problem related to the drainage of the bile from the gall bladder).

If you are not sure if any of these apply to you, talk to your doctor or pharmacist before taking Candesartan cilexetil.

Warnings and precautions

Talk to your doctor before taking Candesartan cilexetil.

•    if you have any heart, liver or kidney problems or are on dialysis.

•    if you have recently had a kidney transplant.

•    if you are vomiting, have recently had severe vomiting, or have diarrhoea.

•    if you have a disease of the adrenal gland called Conn's Syndrome (also called primary hyperaldosteronism).

•    if you have low blood pressure.

•    if you have ever had a stroke.

•    you must tell your doctor if you think you are (or might become) pregnant. Candesartan cilexetil is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see pregnancy section).

Your doctor may want to see you more often and do some tests if you have any of these conditions.

If you are going to have an operation, tell your doctor or dentist that you are taking Candesartan cilexetil. This is because Candesartan cilexetil, when combined with some anaesthetics, may cause a drop in blood pressure.

Children

There is no experience with the use of Candesartan cilexetil in children (below the age of 18 years). Therefore Candesartan cilexetil should not be given to children.

Other medicines and Candesartan cilexetil

Please tell your doctor or pharmacist if you are using, or have recently used, any other medicines, including medicines obtained without a prescription.

Relon 3 ;m

Candesartan cilexetil can affect the way some other medicines work and some medicines can have an effect on Candesartan cilexetil. If you are using certain medicines, your doctor may need to do blood tests from time to time.

In particular, tell your doctor if you are using any of the following medicines:

•    Other medicines to help lower your blood pressure, including beta-blockers, diazoxide and ACE inhibitors such as enalapril, captopril, lisinopril or ramipril.

•    Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, diclofenac, celecoxib or etoricoxib (medicines to relieve pain and inflammation).

•    Acetylsalicylic acid (If you are taking more than 3g each day) (medicine to relieve pain and inflammation).

•    Potassium supplements or salt substitutes containing potassium (medicines that increase the amount of potassium in your blood).

•    Heparin (a medicine for thinning the blood).

•    Water tablets (diuretics).

•    Lithium (a medicine for mental health problems).

Candesartan cilexetil with food and drinks and alcohol

•    You can take Candesartan cilexetil with or without food.

•    When you are prescribed Candesartan cilexetil, discuss with your doctor before drinking alcohol. Alcohol may make you feel faint or dizzy.

Pregnancy and breast-feeding

Pregnancy

You must tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Candesartan cilexetil before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Candesartan cilexetil. Candesartan cilexetil is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.

Breast-feeding

Tell your doctor if you are breast-feeding or about to start breast-feeding. Candesartan cilexetil is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely.

Driving and using machines

Some people may feel tired or dizzy when taking Candesartan cilexetil. If this happens to you, do not drive or use any tools or machines.

Important information about some of the ingredients of Candesartan cilexetil

Candesartan cilexetil contains lactose, which is a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. HOW TO TAKE CANDESARTAN CILEXETIL

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. It is important to keep taking Candesartan cilexetil every day.

You can take Candesartan cilexetil with or without food.

Swallow the tablet with a drink of water.

Try to take the tablet at the same time each day. This will help you to remember to take it.

High blood pressure:

•    The usual dose of Candesartan cilexetil is 8 mg once a day. Your doctor may increase this dose to 16 mg once a day and further up to 32 mg once a day, depending on blood pressure response.