Each 2.8 gram sachet of granules contains:
Sodium Bicarbonate Ph. Eur. 1.26g
Each 10ml bottle of Carbex solution contains:
Citric Acid Ph. Eur. 1g in 10ml
Separate granules and solution for oral administration.
Gas producing agent for double contrast radiography of the gastrointestinal tract. Carbex is given orally.
The contents of one sachet (2.8g) of Carbex granules are placed on the patient's tongue and then immediately washed down with 10ml of the solution. It is recommended that the barium should be swallowed thirty seconds later.
4.4 Special Warnings and Precautions for Use
4.5 Interactions with other Medicaments and other forms of Interaction
4.6 Pregnancy and Lactation
No known effect
4.7 Effects on Ability to Drive and Use Machines
No known effects
4.8 Undesirable Effects
No known effect
5 PHARMACOLOGICAL PROPERTIES
5.1 Pharmacodynamic Properties
Sodium bicarbonate and citric acid react to produce carbon dioxide in the gastrointestinal tract. Simethicone is present to prevent excessive bubble formation during the release of gas.
There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.
Povidone BP Mannitol Ph. Eur.
Methylparaben Ph. Eur.
Propylparaben Ph. Eur.
Saccharin Sodium BP Orange Flavour Purified Water
Shelf life of sachets and solution (unopened): 36 months.
Do not store above 25°C
Carbex is supplied as a pack containing sufficient for one patient treatment. The outer package contains the following:
Part 1: 1 x 2.8g sachets of Carbex granules. The sachet is composed of paper/polyethylene/aluminium foil/surlyn.
Part II: 1 x 10ml bottle of Carbex solution. The bottle is high density polyethylene with a high impact polypropylene screw cap.
Open one sachet of Carbex granules (Part I). Place the granules on the patient’s tongue. Have the patient immediately swallow the complete contents of the 10ml bottle (Part II).
Nordic Pharma Limited 11 Mount Road Feltham TW13 6AR United Kingdom
1 October 2002