Concavit Drops
Each 0.5ml contains: -
Vitamin A BP	5000.00 iu
Calciferol BP	500.00 iu
Vitamin C	50mg
(as Ascorbic Acid BP	19.35mg and
Sodium Ascorbate USP	34.44mg)
Thiamine Hydrochloride	2.00 mg
Riboflavine	1.0 mg
(as Riboflavine Sodium Phosphate BP	1.37 mg)
Pyridoxine Hydrochloride BP	1.00 mg
Nicotinamide BP	12.50 mg
Panthenol	2.0mg

In addition the drops also contain Sodium Edetate, Glycerin, Polysorbate 80, Propylene Glycol, Hydroxybenzoates (Methyl, Ethyl, Propyl and Butyl), Propyl Gallate, Flavouring (Orange Essence & Morella Cherry Essence), Sodium Saccharin, Sorbitol Solution and Water.

Concavit drops is available in packs of 15ml.

Concavit is an oral vitamin supplement.

The product licence holder is Wallace Manufacturing Chemists Ltd., Wallace House, 51-53 Stert Street, Abingdon, Oxfordshire OX14 3JF, United Kingdom and the drops are manufactured by Thorpe Laboratories Ltd., Enterprise Road, Mablethorpe, LincolnshireLN12 1LH, England.

Product Licence number: PL 00400/5010R

Concavit is intended as a multiple vitamin supplement in situations of special dietary need. It is not intended for the correction of specific vitamin deficiencies.

Before you use Concavit

Do not use Concavit to treat vitamin deficiencies caused by inability to absorb the vitamin(s) orally.

Do not use Concavit if:

•    You are hypersensitive to any of the ingredients

•    You have a history of high levels of Vitamins A or D

•    You have bone tumours

•    You have elevated blood calcium levels.

•    You have abnormal metabolic sensitivity to vitamin D Do not take Vitamin A supplements if you are pregnant or likely to become pregnant except on the advice of your doctor or antenatal clinic.

Precautions for the use of Concavit

Do not exceed the stated dose.

Interactions with other medicine

Concavit may react with other medicines you are taking. If you are taking any of the medicines listed then consult your pharmacist or doctor.

■    Contraceptive pills may increase levels of Vitamin A.

■    Agents such as Bile Acid Resins e.g. Cholestyramine and Colestipol impair the absorption of fats including the fat soluble vitamins A and D.

■    Thiazide diuretics and Vitamin D both increase blood calcium levels so when used together very high levels of calcium in the blood may occur.

■    High blood levels of calcium from the vitamin D administration may enhance the toxic effects of glycoside heart drugs (e.g. digoxin).

■    Vitamin D also enhances magnesium absorption.

■    Barbiturates or anticonvulsants may reduce the effects of Vitamin D on the absorption of calcium from the diet and from resorption from the bones.

■    Liquid Paraffin taken orally and other agents that affect the mobility of the gut (e.g. antispasmodics) may interfere with the absorption of the fat soluble vitamins.

■    Pyridoxine reduces the effects of L-dopa (usually prescribed for the treatment of Parkinson’s disease). Your doctor may also prescribe a medicine known as a dopa-decarboxylase inhibitor which helps prevent this interaction.

Dosage

All ages: 0.5ml to be taken by mouth daily.

If you miss a dose take it as soon as you remember unless it is almost time for your next dose. Do not take a double dose.

Overdose

Overdose is only likely to occur if doses in excess of those recommended are taken and/or for prolonged periods. If you have taken too much Concavit Drops then consult your doctor.

Undesirable effects Vitamin A

Vitamin A toxicity initially causing irritability, vomiting, loss of appetite and skin changes has been reported especially in children. With long term vitamin A overdose liver and brain disorders may occur. The symptoms usually disappear after withdrawal of the treatment.

Vitamin D

Vitamin D toxicity causes disturbances of calcium metabolism leading to calcium deposits forming in soft tissue including the lungs and kidneys. Brain and circulatory damage can also occur especially in infants. In infants showing increased Vitamin D sensitivity there is especial risk of elevated blood calcium levels.

Symptoms of elevated blood calcium levels include anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, thirst, increased urine production, drowsiness, confusion, calcium deposits in the kidneys and in severe cases heartbeat disturbances, coma and heart failure.

If you suffer any of these effects or have any other reaction that you believe may be due to taking Concavit then consult your doctor.

Some of the non-active ingredients may also cause undesirable effects. One ingredient is glycerin (sometimes called glycerol). Glycerin is harmful in high doses. It can cause headaches and can cause stomach upsets and diarrhoea.

Storage

Do not use the product after the marked expiry date Store in a cool place Protect from light

Leaflet revision date: 17 April 2009