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Dettol Antiseptic Disinfectant 4.8% W/V Concentrate For Cutaneous Solution

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SUMMARY OF PRODUCT CHARACTERISTICS

1    NAME OF THE MEDICINAL PRODUCT

Dettol Liquid

Dettol Antiseptic Disinfectant 4.8% w/v Concentrate for Cutaneous Solution

2    QUALITATIVE AND QUANTITATIVE    COMPOSITION

Active ingredient    % w/v    Specification

Chloroxylenol    4.8    BP

3    PHARMACEUTICAL FORM

Concentrate for cutaneous solution.

4    CLINICAL PARTICULARS

4.1    Therapeutic indications

Medical - for cuts, bites, abrasions and insect stings.

Personal hygiene - for douching, dandruff; and spots and pimples.

4.2    Posology and method of administration

For external use only.

(a)    Medical uses

For cuts, bites, abrasions and insect stings: wash the area with one tablespoonful of Dettol diluted in a half pint of water and cover with dry gauze or lint.

For urgent application, Dettol may be used undiluted, but not on sensitive skins.

(b)    Personal hygiene

For douching (when medically advised): two teaspoonfuls of Dettol diluted in two pints of warm water.

For dandruff: one tablespoonful of Dettol diluted in one pint of warm water. Saturate hair and scalp for 10 minutes, then shampoo.

For spots and pimples: bathe the affected area daily with one tablespoonful of Dettol diluted in half a pint of warm water (not for eczematous conditions).

4.3    Contraindications

Not applicable.

4.4    Special warnings and precautions for use

For external use only.

If swallowed, wash out mouth and drink plenty of water or milk. If contact is made with eyes, wash thoroughly with cold water. In both cases consult your doctor.

Keep out of the reach of children.

4.5    Interaction with other medicinal products and other forms of interaction

Not applicable.

4.6    Fertility, pregnancy and lactation

Not applicable.

4.7    Effects on ability to drive and use machines

Not applicable.

4.8    Undesirable effects

Not applicable.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard

4.9    Overdose

Not applicable.

5    PHARMACOLOGICAL    PROPERTIES

5.1    Pharmacodynamic properties

Chloroxylenol is a substituted    phenol    which has been widely used for many

years as an ingredient of antiseptic/disinfectant products intended for external use. It is known to be bactericidal in low concentration to a wide range of Gram positive and Gram negative bacteria.

5.2    Pharmacokinetic properties

Chloroxylenol is well-absorbed when applied to the skin. It is extensively metabolised in the body, probably by the liver, and rapidly excreted, mainly in the urine, as sulphate and glucuronide conjugates. Chloroxylenol has a low

systemic toxicity, even at dosage levels many times higher than those likely to be absorbed during normal usage of Dettol Liquid.

5.3 Preclinical safety data

No preclinical findings of relevance have been reported.

6    PHARMACEUTICAL PARTICULARS

6.1    List of excipients

Pine oil

Isopropyl alcohol Castor oil

Caustic soda solution

Caramel

Water

6.2    Incompatibilities

Not applicable.

6.3    Shelf life

Three years.

6.4    Special precautions for storage

There are no special precautions for storage.

6.5    Nature and contents of container

Polypropylene and Polyvinylchloride bottles with polypropylene screw cap with PVdC faced wadding.

Pack sizes: 125, 250, 500, 750, 1000ml.

Plastic Bottles.

Pack Sizes: 2L, 4L and 5L.

6.6    Special precautions for disposal

For external use only.

7    MARKETING AUTHORISATION HOLDER

Reckitt Benckiser (UK) Limited

103-105 Bath Road

Slough

SL13UH United Kingdom

8    MARKETING AUTHORISATION NUMBER(S)

PL 19718/0008

9    DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION

26/11/1986

10    DATE OF REVISION OF THE TEXT

02/02/2015