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Glycerol Blackcurrant Flavour Cough Syrup

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SUMMARY OF PRODUCT CHARACTERISTICS

1 NAME OF THE MEDICINAL PRODUCT

Glycerol Blackcurrant Flavour Cough Syrup

2 QUALITATIVE AND QUANTITATIVE COMPOSITION

Active Ingredient    Quantity per 5 ml

Glycerol    0.75ml

Liquid sugar    1.93ml

(Equivalent to sucrose    1.7g)

Excipient with known effect:

Liquid Glucose    to 5ml

For full list of excipients, see section 6.1.

3 PHARMACEUTICAL FORM

Syrup

A dark red, blackcurrant flavoured syrup.

4 CLINICAL PARTICULARS

4.1 Therapeutic indications

For the relief of irritating, tickling dry coughs and sore throats

4.2 Posology and method of administration

Adults, elderly and children over 5 years: 10ml

Children 1 - 5 years: 5ml

The dose may be repeated three or four times a day.

Children under one year: Not to be given to children under 1 year.

For oral administration.

4.3 Contraindications

Hypersensitivity or intolerance to any of the ingredients.

4.4 Special warnings and precautions for use

Diabetics should take note of the carbohydrate content of this product.

Patients with rare glucose-galactose malabsorption should not take this medicine

Do not give to children under one year.

Keep all medicines out of the reach of children.

4.5 Interaction with other medicinal products and other forms of interaction

No clinically significant interactions known.

4.6 Fertility, Pregnancy and lactation

The safety of this medicine during pregnancy and lactation has not been established, but is not considered to constitute a hazard during these periods.

4.7 Effects on ability to drive and use machines

None stated.

4.8 Undesirable effects

Immune system disorder: hypersensitivity reactions, including anaphylaxis.

4.9 Overdose

Overdosage would not be expected to cause any problems and treatment would be merely symptomatic and supportive.

5.1 Pharmacodynamic properties

Glycerin and sucrose have demulcent properties and will soothe irritated sore throats and possibly block sensory cough receptors within the respiratory tract.

5.2 Pharmacokinetic properties

Glycerin is readily absorbed from the gastrointestinal tract and undergoes extensive metabolism principally in the liver. It may be used in the synthesis of lipids, and is metabolised to glucose or glycogen or oxidised to carbon dioxide and water. It may also be excreted in the urine unchanged.

Sucrose is hydrolysed in the small intestine by the enzyme sucrase to glucose and fructose which are then absorbed.

5.3 Preclinical safety data

There are no preclinical data of relevance to the prescriber which are additional to that already included.

6 PHARMACEUTICAL PARTICULARS

6.1 List of excipients

Citric acid monohydrate Sodium benzoate Anthocyanin

Blackcurrant Flavour 1740.7107 IFF Blackcurrant Juice 1740.1436 IFF Liquid Glucose Purified Water

6.2 Incompatibilities

Not applicable.

6.3


Shelf life

24 months.


6.4


Special precautions for storage

None stated.


6.5

125ml,


Nature and contents of container

150ml or 200ml white flint glass, or amber glass bottle with an aluminium roll-on pilfer-proof cap with a flowed in liner, or a triseal (LDPE/EPE/LDPE) liner.

Alternative caps: A wadless polypropylene tamper evident cap, or a child resistant polypropylene cap with a EPE liner.

A double ended measuring spoon of 2.5ml and 5.0ml capacity may optionally be provided with the product.


6.6


Special precautions for disposal

Not applicable.


7


MARKETING AUTHORISATION HOLDER

McNeil Products Limited Foundation Park Roxborough Way Maidenhead Berkshire SL6 3UG United Kingdom


MARKETING AUTHORISATION NUMBER(S)

PL 15513/0392


DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION

24/11/2014

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DATE OF REVISION OF THE TEXT

16/01/2015