Morphine Sulfate Suppositories 10mg

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In this leaflet:

1.    What Morphine Sulfate Suppositories are and what they are used for

2.    Before you use Morphine Sulfate Suppositories

3.    How to use Morphine Sulfate Suppositories

4.    Possible side effects

5.    How to store Morphine Sulfate Suppositories

6.    Further information

1.    What Morphine Sulfate Suppositories are and what they are used for

Morphine is an alkaloid with pain relieving properties.

Morphine Sulfate Suppositories are used or the relief of severe pain.

2.    Before you use Morphine Sulfate Suppositories

You should not use Morphine Sulfate Suppositories if you:

•    are allergic (hypersensitive) to Morphine Sulfate or to any of the ingredients listed in section 6 of this leaflet

•    are currently suffering from breathing difficulties or you usually suffer from breathing problems such as asthma

•    are suffering from severe stomach pains

•    suffer from problems with your liver

•    suffer from alcoholism

•    are currently taking drugs used to treat depression known as monoamine oxidase inhibitors (MAOIs) or have taken them in the last 2 weeks

•    have suffered a head injury or are experiencing severe and undiagnosed headaches

•    are unable to open your bowels due to a blockage in your intestines (paralytic ileus)

•    have been told you are suffering from a condition known as delayed gastric emptying, the symptoms of which include heartburn, feeling sick or being sick and feeling full quickly whilst eating

•    suffer from severe heart and lung problems

•    suffer from a tumour of the adrenal gland known as phaeochromocytoma

Take special care with Morphine Sulfate Suppositories if you:

•    are about to have an operation to reduce your pain

•    sufferfrom problems with your adrenal glands (adrenocortical insufficiency)

•    suffer from thyroid problems

•    have low blood pressure

•    suffer from liver or kidney disease

•    suffer from problems with your bowel

•    suffer from problems with your prostate

•    suffer from a disorder that causes muscle weakness known as myasthenia gravis

•    are in shock, the symptoms of which include sweating, a fast pulse and cold, clammy skin

•    suffer from fits

•    suffer from problems with your pancreas

•    suffer from an irregular heartbeat

•    have been told you suffer from a severe heart problem known as cor pulmonale

f you are elderly you should take special care when using morphine sulfate suppositories.

f you have any concerns about your treatment with this medicine please discuss this with your doctor.

Taking other medicines

Please tell your doctor, nurse or pharmacist if you are taking, or have recently taken, any other medicine including medicines obtained without prescription.

Please tell your doctor if you are taking any of the following medicines:

•    medicines used to treat severe depression known as monoamine oxidase inhibitors (MAOIs) e.g. moclobemide. Tell your doctor even if you have stopped taking them within the last two weeks

•    medicines used to treat mental disorders (antipsychotics) such as chlorpromazine and haloperidol

•    medicines used to reduce anxiety (anxiolytics) such as diazepam and buspirone

•    medicines used to help you to sleep (hypnotics) such as temazepam and zopiclone

•    CNS depressants (drugs that act on the brain and make you feel drowsy or faint). These include sleeping pills, anti-histamines (medicines used to treat allergies) that make you drowsy, medicines used to treat certain mental disorders, other pain killers or a general anaesthetic.

•    medicines used to treat depression (tricyclic antidepressants) such as amitriptyline and imipramine

•    cimetidine, a medicine used to treat stomach ulcers

•    ciprofloxacin, a medicine used to treat bacterial infections

•    medicines used to treat acid reflux and heartburn e.g. domperidone and metoclopramide

•    esmolol, a medicine used to treat high blood pressure

•    mexiletine, a medicine used to treat an irregular heartbeat

•    ritonavir, a medicine used to treat HIV Using Morphine Sulfate Suppositories with food and drink

You are advised not to drink alcohol during your treatment with this medicine Pregnancy and breast-feeding:

Morphine Sulfate Suppositories should not be used during pregnancy (especially during the first three months) as Morphine is known to cross the placenta.

This medicine should also not be used whilst breast-feeding as Morphine is known to be present in breast milk and it may cause respiratory problems in newborn babies.

Effects on the ability to drive and use machinery:

This medicine may cause drowsiness.

If you are affected do not drive or use machines.

This medicine can affect your ability to drive and operate machinery as it may make you sleepy or dizzy.

•    Do not drive while taking this medicine until you know how it affects you.

•    It is an offence to drive if this medicine affects your ability to drive.

•    However, you would not be committing an offence if:

•    The medicine has been prescribed to treat a medical or dental problem and

•    You have taken it according to the instructions given by the prescriber or in the information provided with the medicine and

• It was not affecting your ability to drive safely

Talk to your doctor or pharmacist if you are not sure whether it is safe for you to drive while taking this medicine.

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