Medine.co.uk

Solvent-Diluent (For Melphalan Injection)

SUMMARY OF PRODUCT CHARACTERISTICS

1.    NAME OF THE MEDICINAL PRODUCT

SOLVENT-DILUENT (for Melphalan Injection)

2 QUALITATIVE AND QUANTITATIVE COMPOSITION

No active ingredient present

3 PHARMACEUTICAL FORM

Liquid for reconstitution of Melphalan

4    CLINICAL PARTICULARS

4.1    Therapeutic indications

The Solvent-Diluent is used to reconstitute Melphalan Injection.

4.2    Posology and method of administration

The reconstituted injection is administered by infusion.

4.3    Contraindications

Not Applicable.

4.4    Special warnings and precautions for use

Not Applicable.

The label for this product will contain the following statements:

Keep out of the reach of children.

Store below 30°C Do not refrigerate.

Protect from light

4.5    Interaction with other medicinal products and other forms of interaction

Not Applicable.

4.6    Fertility, Pregnancy and lactation

Not Applicable.

4.7    Effects on ability to drive and use machines

Not Applicable.

4.8    Undesirable effects

Not Applicable.

4.9    Overdose

Not Applicable.

5    PHARMACOLOGICAL PROPERTIES

5.1    Pharmacodynamic properties

Not Applicable.

5.2    Pharmacokinetic properties

Not Applicable.

5.3    Preclinical safety data

Not Applicable.

6 PHARMACEUTICAL PARTICULARS 6.1 List of excipients

Excipient Sodium citrate

Specification

Ph.Eur

6.2


6.3


6.4


6.5


6.6


7.


8


Propylene glycol Ethanol (96%) Water for injections


Ph.Eur

BP

Ph.Eur


Incompatibilities

Not Applicable.

Shelf life

36 months

Special precautions for storage

Store below 30°C, protect from light, do not refrigerate.

Nature and contents of container

Clear neutral glass vial and chlorobutyl rubber stopper or fluoro-resin butyl rubber stopper with aluminium collar.

Pack size: 10 ml

Special precautions for disposal

Not Applicable.

Marketing Authorisation Holder

Aspen Pharma Trading Limited 3016 Lake Drive,

Citywest Business Campus,

Dublin 24,

Ireland.

MARKETING AUTHORISATION NUMBER(S)

PL 39699/0040

DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION


18 January 2004


10 DATE OF REVISION OF THE TEXT

29/10/2014