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PATIENT INFORMATION LEAFLET

Sumatriptan 50mg Tablets Sumatriptan 100mg Tablets

(Sumatriptan)

What Sumatriptan Tablet is and what it is used for

Your medicine is in the form of a tablet. Sumatriptan succinate is one of a group of medicines called 5HT1 receptor agonists that are used to treat short lived (acute) migraine attacks.

Selective 5HT-1 receptor agonists are believed to work by reducing the size of blood vessels in the head. It is the temporary swelling of these blood vessels that are thought to cause migraines. A migraine causes attacks of headache, sometimes with sickness or other symptoms e.g. some people become sensitive to light or noise.

Sumatriptan Tablets should only be used if there is a clear diagnosis of migraine. Sumatriptan Tablets should not be used to prevent a migraine attack.

What you need to know before you take Sumatriptan Tablet

DO NOT take Sumatriptan Tablets if:

■    you are allergic (hypersensitive) to sumatriptan or to any of the other ingredients of this medicine (see section 6 "Contents of the pack and other information”)

■    you have taken antibiotics called sulphonamides before and suffered an allergic reaction

■    you have heart problems such as heart disease, angina or suffer from hardened arteries

■    you have had a heart attack

■    you have had a stroke in the past or if you have had the symptoms of a stroke, which only lasted a short time and from which you made a complete recovery (transient ischaemic attack)

■    you have severe liver problems

■    you have moderate to severe high blood pressure or mild uncontrolled high blood pressure

■    you are taking other medicines for migraine which contain ergotamine or ergotamine derivatives including methysergide (see 'Other medicines and Sumatriptan')

■    you are taking or have taken within the last 2 weeks, medicines for the treatment of depression or Parkinson's disease called Monoamine Oxidase Inhibitors (MAOIs)

Warnings and precautions

Talk to your doctor before taking Sumatriptan if:

■    you notice pain or a feeling of tightness in your chest and throat. If these symptoms do not pass quickly, tell your doctor immediately

■    you have risk factors for heart disease such as, sugar diabetes, regular cigarette smoker or patients on nicotine substitution therapy. If these risk factors apply to you they are particularly important if you are a man over 40 years old or a postmenopausal woman

■    you have kidney or liver problems

■    you have had fits or epilepsy in the past

Other medicines and Sumatriptan

Tell doctor or pharmacist if you are taking or have recently

taken or might take any other medicines, including those obtained without a prescription. This includes herbal medicines.

In particular, inform your doctor if you are taking the following:

Medicines not to be taken with Sumatriptan

■    other medicines for migraine which contain ergotamine or ergotamine derivatives including methysergide.

You must wait 24 hours after taking ergotamine or ergotamine derivatives before you take Sumatriptan Tablets. If you have taken Sumatriptan Tablets wait at least 6 hours before taking ergotamine or ergotamine derivatives

■    medicines for the treatment of depression or Parkinson's disease called Monoamine Oxidase Inhibitors (MAOIs), such as phenelzine.

Sumatriptan Tablets must not be taken within 2 weeks of stopping therapy with MAOIs

Other medicines which may interact

■    antidepressants called SSRIs (for example citalopram, fluoxetine, fluvoxamine, paroxetine or sertraline) or lithium

■    herbal medicines containing St John's Wort

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

Pregnancy

Do not take Sumatriptan Tablets if you are pregnant, unless your doctor has told you that it is alright for you to do so.

Breast-feeding

Sumatriptan is excreted in breast milk. The amount the child could receive can be reduced if you avoid breast feeding for 12 hours after taking Sumatriptan Tablets. The breast milk should be expressed and discarded during this period.

Driving and using machines

You may suffer dizziness or other related symptoms either due to the migraine itself or the use of these tablets. If affected do not operate machinery or drive.

Sumatriptan tablets contain lactose

If you have been told by the doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

How to take Sumatriptan Tablet

Always take Sumatriptan Tablets exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

■    Sumatriptan Tablets are taken by mouth

■    Swallow the tablet with a glass of water

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