Medine.co.uk

Tranylcypromine 10 Mg Coated Tablets

PATIENT INFORMATION LEAFLET

Revision Date: 16.08.2016 Leaflet Reference: PAR 10


Parnate® 10mg Coated Tablets

(tranylcypromine)

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Keep this leaflet. You may need to read it again.

If you have any further questions, ask your doctor or pharmacist.

This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.


Your medicine is known by the above name, but will be referred to as Parnate0 10mg Tablets throughout this leaflet.

What is in this leaflet:

1.    What Parnate0 10mg Tablets are and what they are used for

2.    What you need to know before you take Parnate® 10mg Tablets

3.    Howto take Parnate® 10mg Tablets

4.    Possible side effects

5.    Howto store Parnate® 10mg Tablets

6.    Contents of the pack and other information

1.    WHAT PARNATE® 10MG TABLETS ARE AND WHAT THEY ARE USED FOR

Parnate® 10mg Tablets contain the active substance tranylcypromine which belongs to a group of antidepressant medicines known as monoamine oxidase inhibitors (MAOIs). It works by stopping the breakdown of two substances in the brain called serotonin and noradrenaline. Your medicine should help bring these substances back to normal levels.

This medicine is used to treat moderate to severe depression in adults. It can also help you if you are having feelings of fear (phobia) which sometimes occurs in depression. This medicine is often used when other types of antidepressant medicines have not worked.

2.    WHAT YOU NEED TO KNOW BEFORE YOU TAKE PARNATE® 10MG TABLETS

Do not take Parnate® 10mg Tablets if:

•    You are allergic to tranylcypromine or any of the other ingredients of this medicine (listed in section 6)

•    You are taking other MAOIs or have taken other MAOIs within the last two weeks

•    You have taken clomipramine or imipramine within the last three weeks or are planning to take them within the next three weeks

•    You suffer from porphyria (which is an inherited disease affecting the nervous system and skin)

•    You have severe heart disease or any disease of the blood vessels of the brain

•    You have pheochromocytoma which is a tumour of the adrenal glands (glands near the kidneys) causing high blood pressure

•    You have been diagnosed with an overactive thyroid gland (a gland in the neck)

•    You have known liver damage or a disorder affecting the blood cells (your doctor will know)

•    You are taking any of the medicines listed under ‘Do not take’ in the Other Medicines and Parnate® 10mg Tablets section of this leaflet.

•    Please tell your doctor if any of the above apply to you, and do not take Parnate® 10mg Tablets.

Warnings and precautions

Talk to your doctor or pharmacist before taking this medicine if you:

Thoughts of suicide and worsening of your depression or anxiety disorder:

If you are depressed and/or have anxiety disorders, you can sometimes have thoughts of harming or killing yourself (see section 4 ‘Possible side effects’). These may be increased when first starting antidepressants, since these medicines all take time to work, usually about two weeks but sometimes longer.

You may be more likely to think like this if you:

■    have previously had thoughts about killing or harming yourself.

■    are a young adult. Information from clinical trials has shown an increased risk of suicidal behaviour in adults aged less than 25 years with psychiatric conditions who were treated with an antidepressant.

If you have thoughts of harming or killing yourself, at anytime, contact your doctor or go to a hospital straight away. You may find it helpful to tell a relative or close friend that you are depressed or have an anxiety disorder, and ask them to read this leaflet. You might ask them to tell you if they think your depression or anxiety is getting worse, or if they are worried about changes in your behaviour.

Children and adolescents

Parnate® 10mg Tablets is not recommended for children under 18 years old (see section 3 ‘Use in children and adolescents’).

Other medicines and Parnate® 10mg Tablets

Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.

DO NOT take Parnate® 10mg Tablets with the following medicines:

■    Medicines called sympathomimetic agents - these include ephedrine, pseudoephedrine, adrenaline and noradrenaline (these may be found in medicines used to treat heart problems and asthma as well as some decongestants and cough/cold remedies) Bupropion, a medicine to help you stop smoking

medicines to control appetite, e.g. amphetamine and fenfluramine medicines that treat Parkinson’s disease, e.g. levodopa dopamine, a medicine used to treat certain heart conditions the pain killers pethidine and nefopam

general anaesthetics such as propofol, which are used in surgery other medicines used to treat depression (e.g. amitriptyline, imipramine, tryptophan)

■    buspirone, used to treat anxiety.

Parnate® 10mg Tablets must be taken with caution if you are taking the following medicines:

■    other MAOIs such as isocarboxazid

■    strong pain killers e.g. codeine

■    medicines to treat seizures/fits, e.g. carbamazepine

■    barbiturates used to treat severe sleeping problems, e.g. amylobarbitone

■    SSRIs such as fluoxetine or sertraline (for depression). Taking your medicine with these products may cause the following serious side effects: sweating, extreme agitation, confusion, muscle stiffness

■    medicines for high blood pressure (e.g. guanethidine, reserpine, methyldopa)

■    medicines to treat diabetes (e.g. insulin, metformin)

■    antihistamines used to treat allergies, e.g. cetirizine.

Consult your doctor before you take Parnate® 10mg Tablets if you are taking or might be taking any of these.

Parnate® 10mg Tablets with food, drink and alcohol

are elderly

have a mild heart problem which restricts your activity suffer from seizures/fits (epilepsy) are due to have surgery in the next few weeks have a history of dependence on drugs or alcohol.

Even though some of the above may be obvious, it is important that your doctor is aware if any of them apply to you.

You should NOT take alcohol (especially red wine) whilst you are taking Parnate® 10mg Tablets. This includes non-alcoholic beer or lager.

Parnate® 10mg Tablets stops the breakdown of a substance called tyramine which is found in large amounts of certain foods. If this substance is not broken down, it can cause very high blood pressure.

So, whilst you are taking Parnate® 10mg Tablets, you should avoid the following foods:

•    Matured cheeses (e.g. Cheddar or processed cheese made from mature cheese)

•    Yeast extracts (e.g. Bovril or Marmite)

•    Meat, fish or poultry which is not fresh or has been pickled

•    Broad bean pods

•    Banana skins.

Pregnancy and breast feeding

If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Parnate® 10mg Tablets should NOT be used during pregnancy or breast feeding unless your doctor thinks it is essential. This medicine may pass into breast milk.

Your doctor will decide whether you should ablactate (gradually reduce) or stop therapy with Parnate® 10mg Tablets. Effects of Parnate® 10mg Tablets on fertility are unknown.

Driving and using machines

Parnate® 10mg Tablets may make you feel drowsy or dizzy or affect your concentration. You should not drive or use machines when you first start to take this medicine until you are certain that you are not getting these side effects. If in any doubt, speak to your doctor before you drive or use machines.

Important information about some of the ingredients of Parnate® 10mg Tablets

This medicine also contains carmoisine (E122) and Ponceau 4R (E124) which may cause allergic reactions.

This medicine also contains sucrose (a sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. HOW TO TAKE PARNATE® 10MG TABLETS

Always take this medicine exactly as your doctor has told you. Do NOT take more than your doctor tells you to. Check with your doctor or pharmacist if you are not sure.

Swallow the tablets whole with a glass of water.

The recommended dose for adults is:

•    One tablet in the morning and one tablet in the afternoon each day

•    Try to take the last dose before 3 o’clock in the afternoon

•    This dose may be increased by your doctor to three tablets a day. Take the extra tablet at mid-day

•    If you are elderly your doctor will usually prescribe you a lower dose.

When you start to feel better, your doctor may change your dose to one tablet a day.

Do NOT take more than three tablets each day unless your doctor tells you to.

Use in children and adolescents

Parnate® 10mg Tablets are not recommended for children under 18 years old (see section 2 ‘Children and adolescents’).

If you take more Parnate® 10mg Tablets than you should:

If you think that you, or any other person, have taken too many tablets, contact your doctor or hospital casualty department immediately. Take any remaining tablets and this leaflet with you so that the medical staff know exactly what you have taken.

If you forget to take your Parnate® 10mg Tablets:

If you miss a dose, wait until your next dose. Do not take the dose you have missed. You can then carry on as before. Do not take more than one dose at a time.

If you stop taking Parnate® 10mg Tablets

Continue to take Parnate® 10mg Tablets even if you no longer feel ill. DO NOT STOP taking this medicine without talking with your doctor first, especially if you have taken large doses for a long time.

When the time comes to stop your doctor will probably decrease your dose gradually as stopping the tablets suddenly may cause ill-effects such as nausea (feeling sick), vomiting (being sick), sweating and difficulty in sleeping. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4.    POSSIBLE SIDE EFFECTS

Like all medicines, Parnate® 10mg Tablets can cause side effects, although not everybody gets them.

If you eat foods or take medicines which interact with the active ingredient tranylcypromine, you may get very high blood pressure (a hypertensive crisis).

If you notice any of the following symptoms please see your doctor immediately:

•    frequent or throbbing headaches, painful or stiff neck, changes in heart rate, pain in the middle of the chest, feeling sick or being sick, sweating, paleness, or flushing of the skin and enlarged pupils which may make bright sunlight uncomfortable. Although very rare, there may be muscle weakness or paralysis (loss of movement) down one side of the body and there have been a few deaths from hypertensive crisis.

•    thoughts of suicide and suicidal behaviour early on in treatment or shortly after stopping treatment (see section 2 Thoughts of suicide and worsening of your depression or anxiety disorder’).

Sometimes patients feel anxious whilst taking this medicine and rarely some patients will become very agitated or irritable. Your doctor may reduce your dose if this happens.

Some patients get low blood pressure and may feel dizzy on standing up. If this continues for a long time, your doctor may stop your medicine.

Other side effects which may occur include:

•    difficulty in sleeping, mild headache, sleepiness, weakness, dizziness, fast heart beat (palpitations), restlessness, dry mouth, blurred vision, feeling sick, water retention or swelling, weight gain, increased appetite, rash and difficulty in passing water.

Rarely some patients experience soreness in the hands and feet, which may be a sign of inflamed nerves.

Rarely, some patients may find the relief of their depression decreases with time and higher doses of the active ingredient, tranylcypromine, are needed to get the same effect.

Very rarely, liver problems (symptoms include yellowing of the skin and the whites of the eyes), bruising and changes in blood have been reported. Therefore, if you get a bad sore throat or high fever or become very tired and pale or notice bruises and nose bleeds, tell your doctor.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse.

This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/vellowcard.

By reporting side effects, you can help provide more information on the safety of this medicine.

5.    HOW TO STORE PARNATE® 10MG TABLETS

Keep this medicine out of the sight and reach of children.

Do not use Parnate® 10mg Tablets after the expiry date which is stated on the carton and label after EXP. The expiry date refers to the last day of that month.

If your tablets are out of date, take them to your pharmacist who will get rid of them safely.

Do not store above 25°C Store in original container in order to protect from light and moisture. Replace cap tightly after use.

Medicines should not be disposed via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. CONTENTS OF THE PACK AND OTHER INFORMATION What Parnate6 10mg Tablets contain:

Each tablet contains tranylcypromine sulphate equivalent to 10mg of tranylcypromine base.

Parnate® 10mg Tablets also contain sucrose, maize starch, calcium sulphate dihydrate (E516), carmellose sodium, magnesium stearate (E470b). The coating contains gelatin, sucrose, docusate sodium, purified talc (E553b), light kaolin (E559), calcium carbonate (E170), ethylcellulose, acacia (E414), carmoisine (E122), ponceau 4R (E124), maize starch, titanium dioxide (E171), carnauba wax (E903) and edible ink [shellac, iron oxide black (E172), soya lecithin (E322) and trace amounts of dimethyl siloxane].

What Parnate® 10mg Tablets look like and contents of the pack

Parnate® 10mg tablets are bi-convex, geranium-red sugar-coated tablets marked with “FW 251” on one side. The tablets are in white plastic containers with a cap and a security tag containing a desiccant cartridge.

Parnate ® 10mg Tablets are available in containers of 28 tablets.

Who manufactured your medicine

Parnate® 10mg tablets are manufactured by Dales Pharmaceuticals Ltd., Snaygill Industrial Estate, Keighly Road, Skipton, North Yorkshire, BD23 2RW, UK. Procured from within the EU and repackaged by Product Licence Holder: Beachcourse Limited, 20 Alliance Court, Alliance Road, London W3 ORB.

PL 16378/0551    |POM|

Revision date: 16.08.2016 Leaflet reference: PAR 10

PATIENT INFORMATION LEAFLET

Revision Date: 16.08.2016 Leaflet Reference: TRAN 10


Tranylcypromine 10mg Coated Tablets

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Keep this leaflet. You may need to read it again.

If you have any further questions, ask your doctor or pharmacist.

This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.


Your medicine is known by the above name, but will be referred to as Tranylcypromine 10mg Tablets throughout this leaflet.

What is in this leaflet:

1.    What Tranylcypromine 10mg Tablets are and what they are used for

2.    What you need to know before you take Tranylcypromine 10mg Tablets

3.    How to take Tranylcypromine 10mg Tablets

4.    Possible side effects

5.    Howto store Tranylcypromine 10mg Tablets

6.    Contents of the pack and other information

1.    WHAT TRANYLCYPROMINE 10MG TABLETS ARE AND WHAT THEY ARE USED FOR

Tranylcypromine 10mg Tablets contain the active substance tranylcypromine which belongs to a group of antidepressant medicines known as monoamine oxidase inhibitors (MAOIs). It works by stopping the breakdown of two substances in the brain called serotonin and noradrenaline. Your medicine should help bring these substances back to normal levels.

This medicine is used to treat moderate to severe depression in adults. It can also help you if you are having feelings of fear (phobia) which sometimes occurs in depression. This medicine is often used when other types of antidepressant medicines have not worked.

2.    WHAT YOU NEED TO KNOW BEFORE YOU TAKE TRANYLCYPROMINE 10MG TABLETS

Do not take Tranylcypromine 10mg Tablets if:

•    You are allergic to tranylcypromine or any of the other ingredients of this medicine (listed in section 6)

•    You are taking other MAOIs or have taken other MAOIs within the last two weeks

•    You have taken clomipramine or imipramine within the last three weeks or are planning to take them within the next three weeks

•    You suffer from porphyria (which is an inherited disease affecting the nervous system and skin)

•    You have severe heart disease or any disease of the blood vessels of the brain

•    You have pheochromocytoma which is a tumour of the adrenal glands (glands near the kidneys) causing high blood pressure

•    You have been diagnosed with an overactive thyroid gland (a gland in the neck)

•    You have known liver damage or a disorder affecting the blood cells (your doctor will know)

•    You are taking any of the medicines listed under ‘Do not take’ in the Other Medicines and Tranylcypromine 10mg Tablets section of this leaflet.

•    Please tell your doctor if any of the above apply to you, and do not take Tranylcypromine 10mg Tablets.

Warnings and precautions

Talk to your doctor or pharmacist before taking this medicine if you:

•    are elderly

•    have a mild heart problem which restricts your activity

•    suffer from seizures/fits (epilepsy)

•    are due to have surgery in the next few weeks

•    have a history of dependence on drugs or alcohol.

Even though some of the above may be obvious, it is important that your doctor is aware if any of them apply to you.

Thoughts of suicide and worsening of your depression or anxiety disorder:

If you are depressed and/or have anxiety disorders, you can sometimes have thoughts of harming or killing yourself (see section 4 ‘Possible side effects’). These may be increased when first starting antidepressants, since these medicines all take time to work, usually about two weeks but sometimes longer.

You may be more likely to think like this if you:

■    have previously had thoughts about killing or harming yourself.

■    are a young adult. Information from clinical trials has shown an increased risk of suicidal behaviour in adults aged less than 25 years with psychiatric conditions who were treated with an antidepressant.

If you have thoughts of harming or killing yourself, at anytime, contact your doctor or go to a hospital straight away. You may find it helpful to tell a relative or close friend that you are depressed or have an anxiety disorder, and ask them to read this leaflet. You might ask them to tell you if they think your depression or anxiety is getting worse, or if they are worried about changes in your behaviour.

Children and adolescents

Tranylcypromine 10mg Tablets is not recommended for children under 18 years old (see section 3 ‘Use in children and adolescents’).

Other medicines and Tranylcypromine 10mg Tablets

Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.

DO NOT take Tranylcypromine 10mg Tablets with the following medicines:

■    Medicines called sympathomimetic agents - these include ephedrine, pseudoephedrine, adrenaline and noradrenaline (these may be found in medicines used to treat heart problems and asthma as well as some decongestants and cough/cold remedies) Bupropion, a medicine to help you stop smoking

medicines to control appetite, e.g. amphetamine and fenfluramine medicines that treat Parkinson’s disease, e.g. levodopa dopamine, a medicine used to treat certain heart conditions the pain killers pethidine and nefopam

general anaesthetics such as propofol, which are used in surgery other medicines used to treat depression (e.g. amitriptyline, imipramine, tryptophan)

■    buspirone, used to treat anxiety.

Tranylcypromine 10mg Tablets must be taken with caution if you are taking the following medicines:

■    other MAOIs such as isocarboxazid

■    strong pain killers e.g. codeine

■    medicines to treat seizures/fits, e.g. carbamazepine

■    barbiturates used to treat severe sleeping problems, e.g. amylobarbitone

■    SSRIs such as fluoxetine or sertraline (for depression). Taking your medicine with these products may cause the following serious side effects: sweating, extreme agitation, confusion, muscle stiffness

■    medicines for high blood pressure (e.g. guanethidine, reserpine, methyldopa)

■    medicines to treat diabetes (e.g. insulin, metformin)

■    antihistamines used to treat allergies, e.g. cetirizine.

Consult your doctor before you take Tranylcypromine if you are taking or might be taking any of these.

Tranylcypromine 10mg Tablets with food, drink and alcohol

You should NOT take alcohol (especially red wine) whilst you are taking Tranylcypromine 10mg Tablets. This includes non-alcoholic beer or lager.

Tranylcypromine 10mg Tablets stops the breakdown of a substance called tyramine which is found in large amounts of certain foods. If this substance is not broken down, it can cause very high blood pressure.

So, whilst you are taking Tranylcypromine 10mg Tablets, you should avoid the following foods:

•    Matured cheeses (e.g. Cheddar or processed cheese made from mature cheese)

•    Yeast extracts (e.g. Bovril or Marmite)

•    Meat, fish or poultry which is not fresh or has been pickled

•    Broad bean pods

•    Banana skins.

Pregnancy and breast feeding

If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Tranylcypromine 10mg Tablets should NOT be used during pregnancy or breast feeding unless your doctor thinks it is essential. This medicine may pass into breast milk.

Your doctor will decide whether you should ablactate (gradually reduce) or stop therapy with Tranylcypromine 10mg Tablets. Effects of Tranylcypromine on fertility are unknown.

Driving and using machines

Tranylcypromine 10mg Tablets may make you feel drowsy or dizzy or affect your concentration. You should not drive or use machines when you first start to take this medicine until you are certain that you are not getting these side effects. If in any doubt, speak to your doctor before you drive or use machines.

Important information about some of the ingredients of Tranylcypromine 10mg Tablets

This medicine also contains carmoisine (E122) and Ponceau 4R (E124) which may cause allergic reactions.

This medicine also contains sucrose (a sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. HOW TO TAKE TRANYLCYPROMINE 10MG TABLETS

Always take this medicine exactly as your doctor has told you. Do NOT take more than your doctor tells you to. Check with your doctor or pharmacist if you are not sure.

Swallow the tablets whole with a glass of water.

The recommended dose for adults is:

•    One tablet in the morning and one tablet in the afternoon each day

•    Try to take the last dose before 3 o’clock in the afternoon

•    This dose may be increased by your doctor to three tablets a day. Take the extra tablet at mid-day

•    If you are elderly your doctor will usually prescribe you a lower dose.

When you start to feel better, your doctor may change your dose to one tablet a day.

Do NOT take more than three tablets each day unless your doctor tells you to.

Use in children and adolescents

Tranylcypromine 10mg Tablets are not recommended for children under 18 years old (see section 2 ‘Children and adolescents’).

If you take more Tranylcypromine 10mg Tablets than you should:

If you think that you, or any other person, have taken too many tablets, contact your doctor or hospital casualty department immediately. Take any remaining tablets and this leaflet with you so that the medical staff know exactly what you have taken.

If you forget to take your Tranylcypromine 10mg Tablets:

If you miss a dose, wait until your next dose. Do not take the dose you have missed. You can then carry on as before. Do not take more than one dose at a time.

If you stop taking Tranylcypromine 10mg Tablets

Continue to take Tranylcypromine 10mg Tablets even if you no longer feel ill. DO NOT STOP taking this medicine without talking with your doctor first, especially if you have taken large doses for a long time.

When the time comes to stop your doctor will probably decrease your dose gradually as stopping the tablets suddenly may cause ill-effects such as nausea (feeling sick), vomiting (being sick), sweating and difficulty in sleeping. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4.    POSSIBLE SIDE EFFECTS

Like all medicines, Tranylcypromine 10mg Tablets can cause side effects, although not everybody gets them.

If you eat foods or take medicines which interact with the active ingredient tranylcypromine, you may get very high blood pressure (a hypertensive crisis).

If you notice any of the following symptoms please see your doctor immediately:

•    frequent or throbbing headaches, painful or stiff neck, changes in heart rate, pain in the middle of the chest, feeling sick or being sick, sweating, paleness, or flushing of the skin and enlarged pupils which may make bright sunlight uncomfortable. Although very rare, there may be muscle weakness or paralysis (loss of movement) down one side of the body and there have been a few deaths from hypertensive crisis.

•    thoughts of suicide and suicidal behaviour early on in treatment or shortly after stopping treatment (see section 2 Thoughts of suicide and worsening of your depression or anxiety disorder’).

Sometimes patients feel anxious whilst taking this medicine and rarely some patients will become very agitated or irritable. Your doctor may reduce your dose if this happens.

Some patients get low blood pressure and may feel dizzy on standing up. If this continues for a long time, your doctor may stop your medicine.

Other side effects which may occur include:

•    difficulty in sleeping, mild headache, sleepiness, weakness, dizziness, fast heart beat (palpitations), restlessness, dry mouth, blurred vision, feeling sick, water retention or swelling, weight gain, increased appetite, rash and difficulty in passing water.

Rarely some patients experience soreness in the hands and feet, which may be a sign of inflamed nerves.

Rarely, some patients may find the relief of their depression decreases with time and higher doses of the active ingredient, tranylcypromine, are needed to get the same effect.

Very rarely, liver problems (symptoms include yellowing of the skin and the whites of the eyes), bruising and changes in blood have been reported. Therefore, if you get a bad sore throat or high fever or become very tired and pale or notice bruises and nose bleeds, tell your doctor.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse.

This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/vellowcard.

By reporting side effects, you can help provide more information on the safety of this medicine.

5.    HOW TO STORE TRANYLCYPROMINE 10MG TABLETS

Keep this medicine out of the sight and reach of children.

Do not use Tranylcypromine 10mg Tablets after the expiry date which is stated on the carton and label after EXP. The expiry date refers to the last day of that month.

If your tablets are out of date, take them to your pharmacist who will get rid of them safely.

Do not store above 25°C Store in original container in order to protect from light and moisture. Replace cap tightly after use.

Medicines should not be disposed via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

What Tranylcypromine 10mg Tablets contain:

Each tablet contains tranylcypromine sulphate equivalent to 10mg of tranylcypromine base.

Tranylcypromine 10mg Tablets also contain sucrose, maize starch, calcium sulphate dihydrate (E516), carmellose sodium, magnesium stearate (E470b). The coating contains gelatin, sucrose, docusate sodium, purified talc (E553b), light kaolin (E559), calcium carbonate (E170), ethylcellulose, acacia (E414), carmoisine (E122), ponceau 4R (E124), maize starch, titanium dioxide (E171), carnauba wax (E903) and edible ink [shellac, iron oxide black (E172), soya lecithin (E322) and trace amounts of dimethyl siloxane].

What Tranylcypromine 10mg Tablets look like and contents of the pack

Tranylcypromine 10mg tablets are bi-convex, geranium-red sugar-coated tablets marked with “FW 251” on one side. The tablets are in white plastic containers with a cap and a security tag containing a desiccant cartridge.

Tranylcypromine 10mg Tablets are available in containers of 28 tablets.

Who manufactured your medicine

Tranylcypromine 10mg tablets are manufactured by Dales Pharmaceuticals Ltd., Snaygill Industrial Estate, Keighly Road,

Skipton, North Yorkshire, BD23 2RW, UK. Procured from within the EU and repackaged by Product Licence Holder: Beachcourse Limited, 20 Alliance Court, Alliance Road, London W3 ORB.

PL 16378/0551    |POM|

Revision date: 16.08.2016 Leaflet reference: TRAN 10

3