Trental 400mg
1. What Trental is and what it is used for
2. Before you take T rental
3. How to take T rental
PACKAGE LEAFLET: INFORMATION FOR THE USER Trental® 400mg
(pentoxifylline)
This product will be referred to as Trental throughout this
leaflet.
Read all of this leaflet carefully before you start taking this
medicine
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
• If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
In this leaflet:
1. What Trental is and what it is used for
2. Before you take Trental
3. How to take Trental
4. Possible side effects
5. How to store Trental
6. Further information
Trental contains a medicine called pentoxifylline.
This belongs to a group of medicines called peripheral vasodilators. It works by increasing the blood flow to the arms and legs.
Trental can be used to treat:
• Peripheral vascular disease (poor circulation to the arms and legs).
• Intermittent claudication (pain on walking or at rest caused by poor circulation to the legs).
Do not take Trental if:
X You are allergic (hypersensitive) to pentoxifylline, other similar medicines such as theophylline or aminophylline or to any of the other ingredients of Trental (see Section 6:
Further Information)
Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
X You have heart problems or have recently had a heart attack X You have severe palpitations (very fast and uneven heartbeats)
X You have had a stroke with bleeding in the brain (cerebral haemorrhage)
X You have had bleeding in the eye (retinal haemorrhage)
Do not take this medicine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Trental.
Take special care with Trental
Check with your doctor or pharmacist before taking your medicine if:
▲ You feel dizzy, light-headed or faint when you stand or sit up too quickly (hypotension)
▲ You have problems with the blood supply to your heart caused by hardening or narrowing of the arteries
▲ You have liver or kidney problems
If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Trental.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines.
This includes medicines you buy without a prescription, including herbal medicines. This is because Trental can affect the way some other medicines work. Also some medicines can affect the way T rental works.
In particular, tell your doctor if you are taking any of the following:
Trental may increase the effect of the following medicines:
• Medicines for diabetes including tablets or insulin
• Medicines for high blood pressure
• Anticoagulants such as warfarin
When taken with Trental, the following medicines increase the chance of you getting side effects:
• Ketorolac used for pain relief
• Theophylline used to treat wheezing or difficulty in breathing
• Ciprofloxacin used to treat bacterial infections
• Medicines used to stop blood clots from forming
• Cimetidine used to treat heartburn and stomach ulcers
Taking Trental with food and drink
Take Trental with or just after meals.
Pregnancy and breast-feeding
You should not take Trental if you are pregnant.
Ask your doctor or pharmacist for advice before taking any medicine.
If you are breast-feeding or planning to breastfeed, talk to your doctor or pharmacist before taking Trental. This is because very small amounts may pass into the mothers' milk.
Driving and using machines
You may feel dizzy while taking this medicine. If this happens, do not drive or use any tools or machines.
Always take Trental exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Taking this medicine
• If you feel the effect of your medicine is too weak or too strong, do not change the dose yourself, but ask your doctor
• Take this medicine by mouth
• S wallow the tablets whole with a drink of water
• Take with or just after a meal
Adults including the elderly
The usual starting dose is 1 tablet (400mg) three times a day. Your doctor may lower your dose to 1 tablet twice a day.
Patients with kidney problems
Your doctor may give you a lower dose if necessary.
Children
T rental is not suitable for use in children.
If you take more Trental than you should
If you take more tablets than you should, talk to a doctor or go to a hospital straight away. The following effects may happen: low blood pressure, feeling sleepy, fits (seizures) or uneven heartbeat.
If you forget to take T rental
Do not take a double dose to make up for a forgotten tablet.
If you stop taking Trental
Keep taking Trental until your doctor tells you to stop taking it.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
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