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Trihexyphenidyl 2mg Tablets Bp

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The dose will be different for different medical conditions and patients. Your doctor has decided the dose which is best for you. Always follow your doctor’s instructions. The pharmacist’s label will tell you how many tablets to take and how often to take them. If you do not understand anything, ask your doctor or pharmacist.

The usual dose starts at 1 - 2mg (half to one 2mg tablet) per day. This may be increased by your doctor gradually to a maximum dose of 20mg

(four 5mg tablets) per day.

Do not stop taking this medicine suddenly as your symptoms may get worse. If your dose needs to be reduced your doctor will reduce the amount you should take gradually.

If you take too many Trihexyphenidyl Tablets

If you think you have taken too many tablets, contact your doctor straight away or go to the nearest hospital casualty department. Take with you any remaining tablets and the pack so that the medicine can be identified.

If you forget to take Trihexyphenidyl Tablets

If you forget to take a dose of this medicine, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next dose at the usual time. DO NOT TAKE TWO DOSES AT THE SAME TIME.

4. possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

30 - 50% of patients may experience dry mouth, constipation, blurred vision, dizziness and stomach upset. If any of the following occur STOP TAKING the tablets IMMEDIATELY and contact your doctor, as they may be signs of an allergic reaction:

• shortness of breath, blocked nose, rash, itching, swollen face or lips (could happen to more than 1 in 100 people, but less than 1 in 10)

The following other side-effects have been reported with

trihexyphenidyl:

Uncommon effects (that could happen to more than 1 in 100people, but less than 1 in 10):

•    difficulty in passing urine

•    faster heart beat

•    nervousness

•    high doses of this medicine may cause excitement, feeling of great happiness, agitation or confusion, hallucinations, restlessness, difficulty sleeping, change in your mental

well-being or you may have paranoid delusions (worry that something bad is happening without any reason). Your memory may also be affected.

Reporting of side effects.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at

www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.

5. HOW TO STORE TRIHEXYPHENIDYL TABLETS

KEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN. Keep the tablets in the pack provided and store in a cool dry place.

Do not take the tablets if the expiry date on the pack has passed.

If you have any medicines that are out of date, return them to your pharmacist for safe disposal.

6. further information Ingredients

Each Trihexyphenidyl 2mg Tablet contains 2mg of trihexyphenidyl hydrochloride.

Other ingredients are magnesium stearate, maize starch, pregelatinised maize starch and lactose.

What Trihexyphenidyl Tablets look like

The tablets are round and white with a breakline on one side. They are available in pack sizes of 28, 30, 42, 50, 56, 60, 84, 90,100, 112, 250, 500 and 1000 tablets. (Not all pack sizes may be marketed).

Who makes this medicine and holds the Product Licence:

The Product Licence Holder is Crescent Pharma Limited, Units 3 & 4, Quidhampton Business Units, Polhampton Lane, Overton, Hampshire, RG25 3ED and the Manufacturer is

Surepharm Services Limited, Bretby, Burton Upon Trent, Staffs, DE15 0YZ.

Date leaflet revised: June 2015

If you would like this leaflet in a different format, please

contact the licence holder at the above address.

PATIENT INFORMATION LEAFLET

TRIHEXYPHENIDYL 2mg Tablets

Please read all of this leaflet carefully before you start taking this medicine.

Keep the leaflet, you may need to read it again.

If you have any questions or are not sure about anything, ask your doctor or pharmacist. This medicine has been prescribed for you. Do not pass it on to others. It may

harm them, even if their symptoms are the same as yours.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

in this leaflet:

1.    What Trihexyphenidyl Tablets are and what they are used for

2.    Before you take Trihexyphenidyl Tablets

3.    How to take Trihexyphenidyl Tablets

4.    Possible side effects

5.    How to store Trihexyphenidyl Tablets

6.    Further information

i. what trihexyphenidyl tablets are and what they are used for

Trihexyphenidyl belongs to a group of medicines called antimuscarinics (sometimes called anticholinergics). It works by correcting a chemical imbalance in the brain that affects the transmission of nerve impulses.

It is used to treat Parkinson’s disease by improving muscle control and reducing stiffness so patients can move more naturally. It is also used to treat abnormal face and body movements, muscle spasms and restlessness caused by certain drugs.

2. before you take trihexyphenidyl tablets Do not take these tablets if:

• you are allergic to trihexyphenidyl hydrochloride or any of the other ingredients in the tablets (see section 6).

(An allergic reaction may be recognised as shortness of breath, blocked nose, rash, itching, swollen face or lips). Check with your doctor before taking these tablets if:

•    you have hardening of the arteries

•    you have ever had a reaction to any other medicine

•    you have high blood pressure

•    you have heart, liver or kidney problems

•    you have an enlarged prostate gland, have bladder problems or have difficulty in passing urine

•    you have glaucoma (increased pressure in the eye)

•    you have a blockage in your stomach or bowel

   you are elderly

   you have a condition called myasthenia gravis (a rare muscle weakness disorder)

•    you experience unusual movements of the face, tongue, arms and legs as this may be a sign of a serious condition known as tardive dyskinesia

   you are pregnant or breast feeding. This medicine should

NOT be taken during breast feeding.

Taking other medicines

Check with your doctor or pharmacist before taking these tablets if you are taking any other medicines, including any that you can buy without a prescription. This is especially important if you are taking:

   nefopam (used for pain relief)

   ketoconazole (used to treat fungal infections)

   disopyramide (used to treat irregular heart beat)

   metoclopramide or domperidone (used to stop you feeling or being sick)

   amantadine or levodopa (used to treat Parkinson’s disease)

•    monoamine oxidase inhibitors (MAOIs) e.g. isocarboxacid or moclobemide or tri-cyclic antidepressants e.g. amitriptyline (for treating depression)

   antihistamines (used to treat allergies)

   phenothiazines e.g. chlorpromazine (used to treat mental illness)

   any other medicines to help your muscles to contract and which are being used to avoid problems following an operation, such as difficulty passing urine or to treat a condition known as myasthenia gravis (e.g. neostigmine, distigmine)

   any medicine you have to dissolve under your tongue e.g. glyceryl trinitrate (used to treat angina)

•    any other anti-muscarinic medicines such as those being used to treat irritable bowel syndrome, stomach or bowel

conditions (e.g. atropine, hyoscine), bladder problems (e.g. darifenacin, oxybutynin) or Parkinson’s disease (e.g. benzatropine, procyclidine). Taking these medicines at the same time may increase the risk of side effects such as dry mouth, difficulty in passing urine and constipation. If you are elderly you may also become confused.

Driving or using machinery

Some people may experience blurred vision or feel dizzy or less alert than usual when they are taking these tablets.

Do not drive or operate machinery if this happens to you. Important information about one of the ingredients of this medicine:

Contains lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. how to take trihexyphenidyl tablets

Swallow the tablets with a drink of water just before or with a meal.

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