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Artelac 3.2 Mg/Ml Eye Drops Solution

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SUMMARY OF PRODUCT CHARACTERISTICS

1    NAME OF THE MEDICINAL PRODUCT

Artelac 3.2 mg/ml Eye Drops Solution

2    QUALITATIVE AND QUANTITATIVE COMPOSITION

Hypromellose 3.2 mg/ml

For full list of excipients, see section 6.1.

3    PHARMACEUTICAL FORM

Eye drops, solution.

Sterile clear solution.

4    CLINICAL PARTICULARS

4.1    Therapeutic indications

Acts as a lubricant and artificial tear in the symptomatic treatment of dehydration of

the cornea and conjunctiva due to impaired lacrimal secretion and functional disorders as a result of topical or systemic diseases, or caused by deficient or incomplete eyelid closure.

4.2    Posology and method of administration

Dosage

Suitable for use in adults and children.

Unless otherwise directed, instil 1 drop into the conjunctival sac (comer of the eye, nearest the nose) 3 to 5 times per day or as required, to provide sufficient lubrication.

Therapy of dry eye syndrome requires an individual dosage regimen.

Administration For ocular use only.

4.3 Contraindications

Hypersensitivity to the active substance (hypromellose) or to any of the excipients.

4.4 Special warnings and precautions for use

Stop treatment and consult a physician if irritation persists or worsens or new eye

signs or symptoms develop.

Wearers of soft contact lenses should remove their lenses before Hypromellose is

administered and should wait for at least 15 minutes before they insert them again.

4.5 Interaction with other medicinal products and other forms of interaction

None.

4.6 Pregnancy and lactation

Hypromellose can be used during pregnancy and lactation.

Hypromellose on instillation may cause a short term blurring of vision when first

used. If affected wait until vision has cleared before driving or operating machinery.

4.8 Undesirable effects

Brief blurred vision or a slight stinging sensation on instilling Hypromellose.

4.9 Overdose

No case of overdose has been reported.

5 PHARMACOLOGICAL PROPERTIES

5.1 Pharmacodynamic properties

Pharmacotherapeutic group:

Ophthalmologicals: other ophthalmologicals ATC code: S01X A20

Hypromellose prolongs adhesion, enhances moistening of the cornea and conjunctiva

and allows for a smoother movement of the conjunctiva over the cornea.

5.2 Pharmacokinetic properties

Hypromellose does not permeate the cornea or reach the systemic circulation via the

ophthalmic vessels.

Preclinical safety data

5.3


Hypromellose has proved to be very well tolerated in local toxicity studies.

6    PHARMACEUTICAL PARTICULARS

6.1    List of excipients

Cetrimide

Disodium Phosphate Dodecahydrate Sodium Dihydrogen Phosphate Dihydrate Disodium Edetate Sorbitol

Water for Injections in Bulk

6.2    Incompatibilities

Not applicable.

6.3    Shelf life

3 years. Discard within 28 days of first opening.

6.4    Special precautions for storage

Protect from light. Store below 25°C.

Sterile until opened. Avoid contamination during use.

6.5


Nature and contents of container

10 ml round transparent white bottle (LDPE) with white dropper plug (LDPE) and white cap (HDPE).

6.6 Special precautions for disposal

Avoid contamination during use. Hypromellose SDU eye drops are sterile until first

opened. For single use only. Each carton contains a patient insert with

instructions

for use.

7 MARKETING AUTHORISATION HOLDER

Bausch & Lomb (UK) Ltd

Bausch &Lomb House 106 London Road Kingston-Upon-Thames Surrey KT2 6TN

UK

8    MARKETING AUTHORISATION NUMBER(S)

PL 03468/0032

9 DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION

02/09/2009

10 DATE OF REVISION OF THE TEXT

28/03/2011